HAPIN Trial

Research suggests that household air pollution exposure experienced during gestation and early life is linked to a range of longer-term outcomes, and that the benefits of reduced exposure will continue even if the intervention ends. Therefore, we are conducting an extended follow-up study to continue to follow HAPIN children at three of the research sites (Guatemala, India and Rwanda) through age 5, to evaluate the effects of the original HAPIN intervention on neurologic and physical development. This follow-up study is funded by the National Institute of Environmental Health Sciences, and is entitled "Assessing the 5-Year Effects of a 500-day Liquefied Petroleum Gas Cooking Intervention: Continued Follow up of Participants from the HAPIN trial".  The work builds on the major investment already made in the HAPIN trial by evaluating whether the benefits of the intervention extend beyond pregnancy and the child’s first year of life, leveraging a well-characterized cohort in 3 diverse settings, providing rigorous and widely generalizable answers to questions important for both science and policy. We are maximizing potential for success by extending our prior research, using an experienced and proven research team with strong and ongoing relationships with participants.